PBRC - Clinical Nutrition Research Unit

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Human Phenotyping Core

Molecular Mechanisms Core

Animal Models & Phenotyping Core

	Human Phenotyping Core	PI
1.	Premier Maintenance Trial (WLM - Weight Loss Maintenance)	Dr. Phillip Brantley
2.	Preventing Obesity-Diet Strategies (POUNDS Lost)	Dr. George Bray
3.	Study of Health Outcomes of Weight Loss (Look AHEAD)	Dr. George Bray
4.	Post-DPP Follow-up Study (DPP-OS)	Dr. George Bray
5.	Chromium and Insulin Action	Dr. William Cefalu
6.	Impact of Diet on Intramyocellular Lipid, Endurance Performace and Insulin Senistivity	Dr. Enette Larson-Meyer
7.	Diet, Genetics and CVD Risk Factor in Blacks (Get READI)	Dr. Michael Lefevre
8.	Metabolic Adaption - Two-year Caloric Restriction (CALERIE)	Dr. Eric Ravussin
9.	Fat Cell Size, Muscle Lipid Infiltration & Insulin Resistance	Dr. Eric Ravussin
10.	Determinants of Human Longevity and Healthy Aging	Dr. Eric Ravussin
11.	Menopause Effect on Obesity, Energy Balance and Insulin	Dr. Steven Smith
12.	Wise Mind: Environmental Approach for Obesity Prevention	Dr. Donald Williamson
13.	Obesity: From Genes to Man	Dr. Phillip Brantley

	Molecular Mechanisms Core	PI
1.	The Agouti-Related Protein and its Role in Human Obesity	Dr. George Argyropoulos
2.	Heritage Family Study, Phase 4: The Genomics Center	Dr. Claude Bouchard
3.	Melancortin-3 Receptor Regulation of Insulin Action	Dr. Andrew Butler
4.	Chromium and Insulin Action	Dr. William Cefalu
5.	Control of Gene Transcription by Essential Fatty Acids	Dr. Thomas Gettys
6.	The Role of Delta-6 and Delta-5 Desaturases	Dr. Thomas Gettys
7.	Circadian Mechanisms Regulating Osteogenesis	Dr. Jeffrey Gimble
8.	Molecular Genetics of Thermogenesis	Dr. Leslie Kozak
9.	Genetics of Developmental Plasticity in the Adipocyte	Dr. Leslie Kozak
10.	Novel Regulation of Adipogenesis: Agouti and Melanocortins	Dr. Randall Mynatt
11.	Role of Poly (ADP-ribosyl) Action in Diabetic Neuropathy	Dr. Irina Obrosova
12.	Gene-Genetics, Fitness, Obesity, and Risk of Hypertension	Dr. Tuomo Rankinen
13.	Metabolic Adaptation - Two-year Caloric Restriction (CALERIE)	Dr. Eric Ravussin
14.	Fat Cell Size, Muscle Lipid Infiltration & Insulin Resistance	Dr. Eric Ravussin
15.	Positional Candidate Gene Analysis for Macronutrient Selection QTL	Dr. Brenda Richards-Smith
16.	Molecular Mechanism of IKK in FFA-associated Insulin Resistance	Dr. Jianping Ye
17.	Enterostatin Regulation of Fat Intake	Dr. Andrew Butler
18.	Obesity: From Genes to Man	Dr. Phillip Brantley
19.	Polygenic Regulation of Murine Obesity	Dr. Aamir Zuberi

	Animal Models and Phenotyping Core	PI
1.	The Agouti-Related Protein and its Role in Human Obesity	Dr. George Argyropoulos
2.	Autonomic Regulation of Food Intake and Metabolism	Dr. Hans-Rudolf Berthoud
3.	Dietary Obesity	Dr. George Bray
4.	Melancortin-3 Receptor Regulation of Insulin Action	Dr. Andrew Butler
5.	Control of Gene Transcription by Essential Fatty Acids	Dr. Thomas Gettys
6.	The Role of Delta-6 and Delta-5 Desaturases	Dr. Thomas Gettys
7.	Molecular Genetics of Thermogenesis	Dr. Leslie Kozak
8.	Novel Regulation of Adipogenesis: Agouti and Melanocortins	Dr. Randall Mynatt
9.	Role of Poly (ADP-ribosyl) Action in Diabetic Neuropathy	Dr. Irina Obrosova
10.	Positional Candidate Gene Analysis for Macronutrient Selection QTL	Dr. Brenda Richards-Smith
11.	Brainstem Esophageal - Gastric Control Reflexes	Dr. Richard Rogers
12.	TNF, Vagal Tone and Gastric Motility	Dr. Richard Rogers
13.	Molecular Mechanism of IKK in FFA-associated Insulin Resistance	Dr. Jianping Ye
14.	Enterostatin Regulation of Fat Intake	Dr. Andrew Butler
15.	Obesity: From Genes to Man	Dr. Phillip Brantley
16.	Polygenic Regulation of Murine Obesity	Dr. Aamir Zuberi