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David Burk, Ph.D.
Assistant Professor-Research

Department/Laboratory:
Cell Biology, Imaging and Culture Core

Phone: (225) 763-2779

Fax: (225) 763-0260

Send E-mail

Education:
M.S. University of Alabama, Tuscaloosa, AL (Biology)
Ph.D. University of Georgia, Athens, GA (Botany)

Research Interests:
Dr. Burk is the director of the Cell Biology and Bioimaging Core at PBRC, which provides access to state of the art imaging, analytical, and histological equipment as well as technical expertise and assistance to researchers at PBRC, LSU's main campus, and outside the LSU university system.

Recent Publications:

  1. Bajpeyi S, Pasarica M, Moro C, Conley K, Jubrias S, Sereda O, Burk DH, Zhang Z, Gupta A, Kjems L, Smith SR.  Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes. J Clin Endocrinol Metab. 2011 Apr;96(4): 1160-8. PMCID: PMC3070252
  2. Salbaum JM, Kruger C, Zhang X, Delahaye NA, Pavlinkova G, Burk DH, Kappen C.  Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy. Diabetologia. 2011;54(7):1909-20. PMCID: PMC3882064
  3. Abuznait AH, Cain C, Ingram D, Burk D, Kaddoumi A. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer’s disease. J Pharm Pharmacol. 2011;63(8):1111-18. PMCID: PMC3163078
  4. Youm YH, Adijiang A, Vandanmagsar B, Burk D, Ravussin A, Dixit VD.  Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage. Endocrinology. 2011;152(11):4039-45. PMCID: PMC3199005
  5. Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J, Ye J.  Angiogenic deficiency and adipose tissue dysfunction are associated with macrophage malfunction in SIRT1-/- mice. Endocrinology. 2012;153(4):1706-16. PMCID: PMC3320251
  6. Pires de Carvalho P, Hamel KM, Duarte R, King AG, Haque M, Dietrich MA, Wu X, Shah F, Burk D, Reis RL, Rood J, Zhang P, Lopez M, Gimble JM, Dasa V. Comparison of infrapatellar and subcutaneous adipose tissue stromal vascular fraction and stromal/stem cells in osteoarthritic subjects. J Tissue Eng Regen Med. 2014 Oct;8(10):757-62. PMID: 22807102
  7. Silvers W, Prasai B, Burk DH, Brown ML, McCarley RL. Profluorogenic reductase substrate for rapid, selective, and sensitive visualization and detection of human cancer cells that overexpress NQO1. Journal of the American Chemical Society. 2013;135(1):309-14. PMID: 23198810
  8. Lackey DE, Burk DH, Ali MR, Mostaedi R, Smith WH, Park J, Scherer PE, Seay SA, McCoin CS, Bonaldo P, Adams SH. Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. Am J Physiol Endocrino Metab. 2014 Feb;306(3):E233-46. PMCID: PMC3920015
  9. Tchoukalova YD, Krishnapuram R, White UA, Burk D, Fang X, Nijland MJ, Nathanielsz PW. Fetal baboon sex specific outcomes in adipocyte differentiation at 0.9 gestation in response to moderate maternal nutrient reduction. Int J Obes (Lond). 2014 Feb;38(2):224-30. PMCID: PMC3883997
  10. Tam CS, Covington JD, Bajpeyi S, Tchoukalova Y, Burk D, Johannsen DL, Zingaretti MC, Cinti S, Ravussin E. Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling. J Clin Endocrinol Metab. 2014 May;99(5):1749-57. PMCID: PMC4010691
  11. Covington JD, Bajpeyi S, Moro C, Tchoukalova YD, Ebenezer PJ, Burk DH, Ravussin E, Redman LM. Potential effects of aerobic exercise on the expression of perilipin 3 in the adipose tissue of women with polycystic ovary syndrome: a pilot study. Eur J Endocrinol. 2015 Jan;172(1):47-58. PMCID: PMC4247800